Lamport Lecture: Kathleen Cullen, PhD (Johns Hopkins University)

Predictive Neural Computations for Self-Motion

How does the brain distinguish self-generated motion from motion imposed by the external world? In this talk, I will describe how predictive neural computations shape sensory processing during natural self-motion. Using a combination of systems neurophysiology, computational modeling, and behavior, our work focuses on vestibular, cerebellar, and thalamocortical circuits operating in closed-loop interactions with the environment. I will show how internal predictions dynamically modulate neural responses, suppressing predictable self-generated input while preserving sensitivity to unexpected motion. I will conclude by discussing implications for perception, motor control, and neuroprosthetic design.

Dr. Kathleen Cullen, PhD is a professor of Neuroscience, Otolaryngology, and Biomedical Engineering at John Hopkins University.

https://www.bme.jhu.edu/people/faculty/kathleen-cullen/