NBIO Presents: Travis Rotterman, PhD (Boston University)

Spinal motor circuits reorganization in response to peripheral neuropathy

Peripheral neuropathy encompasses a constellation of injuries and diseases that lead to peripheral axon degeneration, a process commonly referred to as Wallerian degeneration. This pathological axonal loss disrupts sensory-motor integration and gives rise to an array of debilitating symptoms such interjoint discoordination, postural instability, and ataxia. In this talk I will present several ongoing projects investigating how peripheral nerve damage drives reorganization of spinal motor circuits, as well as strategies we are exploring to rescue synaptic connectivity and ultimately improving functional outcomes.

Health Sciences G328 and Zoom