BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//UW Neurobiology &amp; Biophysics - ECPv6.15.18//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-ORIGINAL-URL:https://nbio.uw.edu
X-WR-CALDESC:Events for UW Neurobiology &amp; Biophysics
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:America/Los_Angeles
BEGIN:DAYLIGHT
TZOFFSETFROM:-0800
TZOFFSETTO:-0700
TZNAME:PDT
DTSTART:20250309T100000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0700
TZOFFSETTO:-0800
TZNAME:PST
DTSTART:20251102T090000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:-0800
TZOFFSETTO:-0700
TZNAME:PDT
DTSTART:20260308T100000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0700
TZOFFSETTO:-0800
TZNAME:PST
DTSTART:20261101T090000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:-0800
TZOFFSETTO:-0700
TZNAME:PDT
DTSTART:20270314T100000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0700
TZOFFSETTO:-0800
TZNAME:PST
DTSTART:20271107T090000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20260528T093000
DTEND;TZID=America/Los_Angeles:20260528T103000
DTSTAMP:20260407T174133
CREATED:20250909T201041Z
LAST-MODIFIED:20260403T173132Z
UID:10000106-1779960600-1779964200@nbio.uw.edu
SUMMARY:NBIO Presents: Marius Pachitariu (Janelia Research Campus)
DESCRIPTION:Linking neural representations to behavior using generalization\nSensory-guided decisions are the result of sensorimotor transformations across many brain areas. Recent studies have localized the motor components of these transformations using correlations between brain-wide neural activity and behavior. It has been more difficult to localize sensory computations with the same approach\, as it requires pushing animal performance close to psychophysical thresholds\, which is typically not feasible. Here we developed a new approach for linking sensory computations to behavior by training mice to discriminate between two stimuli and testing their responses to new stimuli. We then calculated the similarity of neural representations between train and test stimuli\, using recordings of over 50\,000 simultaneously-recorded neurons from 9 primary and higher-order visual areas (HVAs) and across cortical depths. We found that neural discrimination on the test images but not the train images correlated with the behavioral discrimination of the animals\, across a large number of stimulus pairs and animals. The link between neural and behavioral performance was highest in the medial HVAs\, suggesting this region as a critical component of sensory transformations and generalization.
URL:https://nbio.uw.edu/event/nbio-presents-marius-pachitariu-janelia-research-campus/
LOCATION:Health Sciences G-328
CATEGORIES:Seminar
ATTACH;FMTTYPE=image/jpeg:https://nbio.uw.edu/wp-content/uploads/2025/03/20240420_Admitted-Student-Day_002-e1764184928561.jpeg
ORGANIZER;CN="UW NBIO":MAILTO:nbio@uw.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20260609T000000
DTEND;TZID=America/Los_Angeles:20260609T235959
DTSTAMP:20260407T174133
CREATED:20251126T192949Z
LAST-MODIFIED:20251126T192949Z
UID:10000119-1780963200-1781049599@nbio.uw.edu
SUMMARY:Wayne E. Crill Endowed Lecture: Kristen Brennand\, PhD (Yale University)
DESCRIPTION:Title and abstract coming soon!
URL:https://nbio.uw.edu/event/wayne-e-crill-endowed-lecture-kristen-brennand-phd-yale-university/
LOCATION:TBA
CATEGORIES:Seminar
ATTACH;FMTTYPE=image/webp:https://nbio.uw.edu/wp-content/uploads/2025/11/brennand-e1764185349396.webp
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20260611T093000
DTEND;TZID=America/Los_Angeles:20260611T103000
DTSTAMP:20260407T174133
CREATED:20250909T184606Z
LAST-MODIFIED:20260403T184125Z
UID:10000108-1781170200-1781173800@nbio.uw.edu
SUMMARY:NBIO Presents: Kara Marshall\, PhD (Baylor College of Medicine)
DESCRIPTION:Seminar Information coming soon!
URL:https://nbio.uw.edu/event/nbio-presents-kara-marshall-baylor-college-of-medicine/
LOCATION:Health Sciences G-328
CATEGORIES:Seminar
ATTACH;FMTTYPE=image/jpeg:https://nbio.uw.edu/wp-content/uploads/2025/10/20231114_November-Campus-Fall-Colors_1126-e1764185509834.jpg
ORGANIZER;CN="UW NBIO":MAILTO:nbio@uw.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20260618T093000
DTEND;TZID=America/Los_Angeles:20260618T103000
DTSTAMP:20260407T174133
CREATED:20251126T193440Z
LAST-MODIFIED:20260403T184323Z
UID:10000123-1781775000-1781778600@nbio.uw.edu
SUMMARY:NBIO Presents: Hernandez Moura Silva\, PhD (Ragon Institute of MGH\, MIT and Harvard)
DESCRIPTION:Ironing Out the Ferrostatic Role of Vasculature Associated Macrophages\nIron is an essential micronutrient required by nearly all living organisms\, and maintaining its homeostasis represents a fundamental biological challenge across multiple levels\, from individual cells to entire tissues and the whole organism. We propose that local iron regulation within adipose tissue is centrally coordinated by vasculature-associated\nmacrophages (VAMs)\, a specialized population of resident tissue macrophages closely associated with the vasculature and known to perform key homeostatic functions. While VAMs and other resident tissue macrophages have been historically linked to host defense/innate immunity\, there is a major gap in our understanding of their diverse functions beyond immunity\, and how their dysfunction drives the progression of chronic inflammatory diseases. Gene expression profiling reveals that VAMs express a comprehensive suite of genes involved in iron import\, export\, processing\, and storage. Our data further demonstrate that VAMs are the most efficient cell type within adipose tissue at importing transferrin-bound iron from the circulation and also function as significant intracellular iron reservoirs. Based on these findings\, we demostrate that VAMs act as central regulators of adipose tissue iron content\, continuously sensing local demand and modulating iron availability to support tissue homeostasis.
URL:https://nbio.uw.edu/event/nbio-presents-hernandez-moura-silva/
LOCATION:Health Sciences G-328
CATEGORIES:Seminar
ATTACH;FMTTYPE=image/jpeg:https://nbio.uw.edu/wp-content/uploads/2025/11/Hernandez_Moura_Silva-Big-e1764185628791.jpg
ORGANIZER;CN="UW NBIO":MAILTO:nbio@uw.edu
END:VEVENT
END:VCALENDAR