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DTSTART;TZID=America/Los_Angeles:20260507T093000
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SUMMARY:NBIO Presents: Jean-Claude Béïque\, PhD (University of Ottawa)
DESCRIPTION:A tale of serotonin’s value: from release dynamics to behavioral regulation
URL:https://nbio.uw.edu/event/nbio-presents-jean-claude-beique-phd-university-of-ottawa/
LOCATION:Health Sciences G-328
CATEGORIES:Seminar
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DTSTART;TZID=America/Los_Angeles:20260514T093000
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SUMMARY:NBIO Presents: Nanthia Suthana\, PhD (Duke University)
DESCRIPTION:Neural Dynamics of Human Memory in Naturalistic Environments\nUnderstanding how the human brain supports memory in real-world settings remains a central challenge in neuroscience. In this talk\, I will present work combining intracranial recordings\, wearable sensing\, and immersive paradigms to study memory during naturalistic behavior. We recorded activity from the human medial temporal lobe while participants navigated real and virtual environments alongside measurements of eye movements and behavior. Neural activity exhibited structured dynamics linked to memory-guided exploration\, including coordination with eye movements and representations of position along remembered routes\, with consistent organization across real and imagined navigation. Extending this framework\, I will present findings from naturalistic fear conditioning paradigms\, demonstrating how memory-related neural dynamics are shaped by emotional learning. I will discuss how these insights can be leveraged to decode and modulate maladaptive memory processes\, with implications for developing closed-loop neurostimulation approaches for disorders such as post-traumatic stress disorder.
URL:https://nbio.uw.edu/event/nbio-presents-nanthia-suthana-phd-duke-university/
LOCATION:Health Sciences G-328
CATEGORIES:Seminar
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ORGANIZER;CN="UW NBIO":MAILTO:nbio@uw.edu
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DTSTART;TZID=America/Los_Angeles:20260521T093000
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CREATED:20251016T204603Z
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SUMMARY:NBIO Presents: Jason Shepherd\, PhD (University of Utah)
DESCRIPTION:Seminar information coming soon! \n Health Sciences G328 and Zoom
URL:https://nbio.uw.edu/event/nbio-presents-jason-shepherd-phd-university-of-utah/
LOCATION:Health Sciences G-328
CATEGORIES:Seminar
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ORGANIZER;CN="UW NBIO":MAILTO:nbio@uw.edu
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DTSTART;TZID=America/Los_Angeles:20260528T093000
DTEND;TZID=America/Los_Angeles:20260528T103000
DTSTAMP:20260424T213542
CREATED:20250909T201041Z
LAST-MODIFIED:20260403T173132Z
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SUMMARY:NBIO Presents: Marius Pachitariu (Janelia Research Campus)
DESCRIPTION:Linking neural representations to behavior using generalization\nSensory-guided decisions are the result of sensorimotor transformations across many brain areas. Recent studies have localized the motor components of these transformations using correlations between brain-wide neural activity and behavior. It has been more difficult to localize sensory computations with the same approach\, as it requires pushing animal performance close to psychophysical thresholds\, which is typically not feasible. Here we developed a new approach for linking sensory computations to behavior by training mice to discriminate between two stimuli and testing their responses to new stimuli. We then calculated the similarity of neural representations between train and test stimuli\, using recordings of over 50\,000 simultaneously-recorded neurons from 9 primary and higher-order visual areas (HVAs) and across cortical depths. We found that neural discrimination on the test images but not the train images correlated with the behavioral discrimination of the animals\, across a large number of stimulus pairs and animals. The link between neural and behavioral performance was highest in the medial HVAs\, suggesting this region as a critical component of sensory transformations and generalization.
URL:https://nbio.uw.edu/event/nbio-presents-marius-pachitariu-janelia-research-campus/
LOCATION:Health Sciences G-328
CATEGORIES:Seminar
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