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X-WR-CALDESC:Events for UW Neurobiology & Biophysics
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SUMMARY:NBIO Presents:  Travis Rotterman\, PhD (Boston University)
DESCRIPTION:Spinal motor circuits reorganization in response to peripheral neuropathy\nPeripheral neuropathy encompasses a constellation of injuries and diseases that lead to peripheral axon degeneration\, a process commonly referred to as Wallerian degeneration. This pathological axonal loss disrupts sensory-motor integration and gives rise to an array of debilitating symptoms such interjoint discoordination\, postural instability\, and ataxia. In this talk I will present several ongoing projects investigating how peripheral nerve damage drives reorganization of spinal motor circuits\, as well as strategies we are exploring to rescue synaptic connectivity and ultimately improving functional outcomes. \n Health Sciences G328 and Zoom
URL:https://nbio.uw.edu/event/nbio-presents-travis-rotterman-boston-university/
LOCATION:Health Sciences G-328
CATEGORIES:Seminar
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SUMMARY:NBIO Presents: Rebecca Shansky\, PhD (Northeastern University)
DESCRIPTION:Prefrontal Circuit Mechanisms Driving Sex Differences in Defensive Responding\nMy lab works to identify sex differences in brain organization that underlie variation in defensive responding. We find that in Pavlovian fear conditioning paradigms\, females are more likely than males to engage active\, escape-like conditioned responses (“darting”) that may be linked to pain processing cortical circuitry. Recently\, our work has focused on connectivity between the anterior cingulate and infralimbic regions of the prefrontal cortex and longitudinal columns of the periaqueductal gray. We use a combination of tract tracing\, immunohistological\, chemogenetic\, and RNAscope techniques to map gene expression and manipulate activity in these circuits\, finding novel sex differences in structure and function as they relate to behavioral outcomes.  \n Health Sciences G328 and Zoom
URL:https://nbio.uw.edu/event/nbio-presents-rebecca-shansky-phd-northeastern-university/
LOCATION:Health Sciences G-328
CATEGORIES:Seminar
ATTACH;FMTTYPE=image/jpeg:https://nbio.uw.edu/wp-content/uploads/2025/09/shansky_rebecca-e1772214337176.jpg
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DTSTART;TZID=America/Los_Angeles:20260319T093000
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SUMMARY:NBIO Presents: Jayeeta Basu\, PhD (New York University)
DESCRIPTION:Cortico-Hippocampal Circuit Interactions in Shaping Learning and Memory Representations\nFlexibility and stability of neuronal ensembles are crucial features of brain function. Little is known about how these properties of local circuits are influenced by long-range inputs. We show\, in mice\, that lateral entorhinal cortex glutamatergic  and GABAergic  projections to CA3 recruit specific microcircuits that conjunctively provide stability to neuronal ensembles\, thereby supporting learning. Furthermore\, circuit mapping and manipulations of hippocampal back-projections to entorhinal cortex in mice show anatomically and functionally distinct hippocampal feedback pathways to deep and superficial layers of the medial entorhinal cortex that differentially modulate excitation-inhibition dynamics\, plasticity\, and novelty driven behavioral output. \n  \n Health Sciences G 328 and Zoom
URL:https://nbio.uw.edu/event/jayeeta-basu-new-york-university/
LOCATION:Health Sciences G-328
CATEGORIES:Seminar
ATTACH;FMTTYPE=image/jpeg:https://nbio.uw.edu/wp-content/uploads/2026/02/basuj01-hero-e1770318502144.jpg
ORGANIZER;CN="UW NBIO":MAILTO:nbio@uw.edu
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