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X-WR-CALNAME:UW Neurobiology &amp; Biophysics
X-ORIGINAL-URL:https://nbio.uw.edu
X-WR-CALDESC:Events for UW Neurobiology &amp; Biophysics
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DTSTART;TZID=America/Los_Angeles:20251003T110000
DTEND;TZID=America/Los_Angeles:20251003T120000
DTSTAMP:20260422T003519
CREATED:20250929T175316Z
LAST-MODIFIED:20250929T175316Z
UID:10000114-1759489200-1759492800@nbio.uw.edu
SUMMARY:NAPE Center Seminar Series: Larry Zweifel\, PhD (UW Psychiatry & Behavioral Sciences)
DESCRIPTION:“Molecular approaches for resolving the regulation of the midbrain dopamine system”\nWe have developed multiple molecular approaches to perform comprehensive analysis of the genetic heterogeneity midbrain dopamine neurons\, the circuits that control them\, the signaling pathways that regulate them\, and the ion channels that give them their signature encoding properties. I will summarize our current views on how the system is organized to mediate its many functions. \n  \n Health Sciences K069
URL:https://nbio.uw.edu/event/nape-center-seminar-series-larry-zweifel-phd-uw-psychiatry-behavioral-sciences/
LOCATION:Magnuson Health Sciences Center\, University of Washington\, NE Pacific Street\, Seattle\, WA\, 98195\, United States
ATTACH;FMTTYPE=image/png:https://nbio.uw.edu/wp-content/uploads/2025/09/Zweifel_Larry-e1759168346520.png
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20251003T150000
DTEND;TZID=America/Los_Angeles:20251003T160000
DTSTAMP:20260422T003519
CREATED:20250929T180004Z
LAST-MODIFIED:20250929T180004Z
UID:10000115-1759503600-1759507200@nbio.uw.edu
SUMMARY:CNC Presents: Farzaneh Najafi\, PhD (Georgia Institute of Technology)
DESCRIPTION:“Temporal signaling\, not predictive processing\, shapes cell type specific dynamics in visual and parietal cortex”\nNeural activity following regular sensory events can reflect either elapsed time since the previous event (temporal signaling) or temporal predictions and prediction errors about the next event (temporal predictive processing). These mechanisms are often confounded\, yet dissociating them is essential for understanding neural circuit computations. We addressed this by performing two-photon calcium imaging from distinct cell types (excitatory\, VIP and SST) in layer 2/3 of visual (VIS) and posterior parietal cortex (PPC)\, while awake mice passively viewed audio-visual stimuli under temporal contexts with different inter-stimulus interval (ISI) distributions. Computational modeling revealed distinct functional clusters of neurons\, including stimulus-activated (ramp-down) and stimulus-inhibited (ramp-up) categories\, with distinct kinetics and area/cell-type biases. Importantly\, all functional clusters were invariant to temporal predictability\, shifted immediately when temporal statistics changed\, and were identical between naive and experienced mice. Population decoding revealed that clusters with heterogeneous kinetics differed in how well they represented interval information\, such that together they tiled elapsed time and produced a distributed\, learning-independent population code for time. These results provide strong evidence against temporal predictive processing in Vis/PPC under passive conditions and instead demonstrate intrinsic coding of interval timing\, redefining the mechanistic origin of ramping and omission-related activity in sensory cortex. We discuss how these dynamics align with stimulus-reset attractor frameworks\, and propose that temporal predictive processing is more likely implemented in other circuits or recruited in Vis/PPC during task-engaged behavior. \n Health Sciences G328
URL:https://nbio.uw.edu/event/cnc-presents-farzaneh-najafi-phd-georgia-institute-of-technology/
LOCATION:Magnuson Health Sciences Center\, University of Washington\, NE Pacific Street\, Seattle\, WA\, 98195\, United States
CATEGORIES:Seminar
ATTACH;FMTTYPE=image/png:https://nbio.uw.edu/wp-content/uploads/2025/09/Screenshot-2025-09-29-at-10.57.39-AM-e1759168777621.png
ORGANIZER;CN="UW Computational Neuroscience Center (CNC)":MAILTO:compneuro@u.washington.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20251016T093000
DTEND;TZID=America/Los_Angeles:20251016T103000
DTSTAMP:20260422T003519
CREATED:20250905T204653Z
LAST-MODIFIED:20260401T171618Z
UID:10000083-1760607000-1760610600@nbio.uw.edu
SUMMARY:NBIO Presents:  Martha Bagnall\, PhD (Washington University in St. Louis School of Medicine)
DESCRIPTION:“Sensorimotor circuits in the larval zebrafish”\n Health Sciences G328 and Zoom \n 
URL:https://nbio.uw.edu/event/nbio-presents-martha-bagnall-phd-washington-university-school-of-medicine-sensorimotor-circuits-in-the-larval-zebrafish/
LOCATION:Magnuson Health Sciences Center\, University of Washington\, NE Pacific Street\, Seattle\, WA\, 98195\, United States
CATEGORIES:Seminar
ATTACH;FMTTYPE=image/jpeg:https://nbio.uw.edu/wp-content/uploads/2025/09/Martha-Bagnall-1-copy-scaled-e1758566122449.jpg
ORGANIZER;CN="UW NBIO":MAILTO:nbio@uw.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20251017T110000
DTEND;TZID=America/Los_Angeles:20251017T120000
DTSTAMP:20260422T003519
CREATED:20251016T193602Z
LAST-MODIFIED:20251016T194554Z
UID:10000116-1760698800-1760702400@nbio.uw.edu
SUMMARY:NAPE Center Presents: Jose Moron- Concepcion\, PhD (Washington Univ. in St. Louis)
DESCRIPTION:“The role of sex and ovarian hormones in pain-induced facilitation of opioid intake”\nOpioid analgesics can alleviate pain symptoms but also have considerable addiction potential. Endogenous opioids and opioid analgesics alike also modulate reward\, stress and negative affect –processes typically dysregulated in drug addiction. Dr. Moron-Concepcion will present findings on how inflammatory pain increases fentanyl self-administration in rodents\, with a focus on sex differences and ovarian hormones. \nHealth Sciences K-069
URL:https://nbio.uw.edu/event/nape-center-presents-jose-moron-concepcion-phd-washington-univ-in-st-louis/
LOCATION:Health Sciences K-069
CATEGORIES:Seminar
ATTACH;FMTTYPE=image/jpeg:https://nbio.uw.edu/wp-content/uploads/2025/10/josehead-e1760643355262.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20251022T190000
DTEND;TZID=America/Los_Angeles:20251022T210000
DTSTAMP:20260422T003519
CREATED:20251016T200744Z
LAST-MODIFIED:20251016T200956Z
UID:10000117-1761159600-1761166800@nbio.uw.edu
SUMMARY:Neuroscience\, AI\, and Society: Justin Smith-Ruiu "How to Survive Death: Moral personhood and the limits of the continuity-of-consciousness argument"
DESCRIPTION:How to Survive Death: Moral personhood and the limits of the continuity-of-consciousness argument\nPhilosophers habitually speak of consciousness-uploading and self-uploading as if these were the same thing. In so doing they take for granted the correctness of a broadly Lockean account of personal identity\, according to which I remain the same person from moment to moment\, or perhaps someday from eon to eon\, in virtue of the continuity of conscious memory. Woody Allen\, too\, was following in Locke’s footsteps when he joked: “I do not want to live on in the hearts of my countrymen\, I want to live on in my apartment.” But is ongoing temporal duration from a distinct node of subjective experience really the only way to keep on being a person? Cross-cultural considerations show that many human groups make use of extremely low-tech devices for personhood-uploading —effigies\, story-boards\, tree-trunks—\, and they hardly expect these objects\, after the transfer of the deceased kin’s identity into them\, to pass the Turing test or to display any observable signs of consciousness at all. “Yes\, but they’re just imagining things\,” you’ll say. Fair enough\, but perhaps we are as well. If we are ever going to succeed at exploiting substrate-neutrality to evade or postpone mortality\, it will be necessary not only to follow the right roadmap towards whole-brain emulation in effecting a high-fidelity transfer of consciousness from one substrate to another. It will also be necessary to examine our longstanding presumption\, these days proliferated almost entirely without argument\, that personhood and consciousness are identical. In this talk I will make a first stab at just such an examination\, drawing in particular on the work of Bostrom\, Chalmers\, Parfit\, and Charles Taylor\, as well as on what I take to be salient examples of radically different conceptions of personhood from the ethnographic and historical record of human representations of reality and of our place in it.
URL:https://nbio.uw.edu/event/cnc-presents-justin-smith-ruiu-university-of-paris/
LOCATION:Foege Genome Sciences Auditorium S-060\, 3720 15th Ave NE\, Seattle\, WA\, 98195\, United States
CATEGORIES:Seminar
ATTACH;FMTTYPE=image/png:https://nbio.uw.edu/wp-content/uploads/2025/10/Screenshot-2025-10-16-at-1.05.26-PM.png
ORGANIZER;CN="UW Computational Neuroscience Center (CNC)":MAILTO:compneuro@u.washington.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20251023T093000
DTEND;TZID=America/Los_Angeles:20251023T103000
DTSTAMP:20260422T003519
CREATED:20250905T210051Z
LAST-MODIFIED:20260401T172055Z
UID:10000084-1761211800-1761215400@nbio.uw.edu
SUMMARY:NBIO Presents: Greg Field\, PhD (UCLA)
DESCRIPTION:This seminar is co-sponsored by the Vision Training Grant.\n“Efficient coding and early visual processing: new insights into signal processing and cell type diversity”\nEfficient coding predicts much about early sensory processing\, particularly in the visual system. However\, the impressive diversity of cell types and visual receptive field properties present in the retina have\, thus far\, not been predicted or explained by the theory. Perhaps this is one reason many visual neuroscientist continue to think about visual processing more in terms of labeled lines and cell types serving the needs of specific behavioral niches — e.g.\, ‘looming’ cells for detecting looming predators. I will discuss work from my lab as well as my collaborator\, John Pearson\, that shows the impressive predictive power of efficient coding theory and paints a possible way forward for understanding the origin and diversity of cell types in the early visual system. \n Health Sciences G328 and Zoom
URL:https://nbio.uw.edu/event/nbio-presents-greg-field-phd-duke-university-efficient-coding-and-early-visual-processing-new-insights-into-signal-processing-and-cell-type-diversity/
LOCATION:Health Sciences G-328
CATEGORIES:Seminar
ATTACH;FMTTYPE=image/jpeg:https://nbio.uw.edu/wp-content/uploads/2025/09/Field_Greg-scaled-e1758566415134.jpg
ORGANIZER;CN="UW NBIO":MAILTO:nbio@uw.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20251030T093000
DTEND;TZID=America/Los_Angeles:20251030T103000
DTSTAMP:20260422T003519
CREATED:20250905T211255Z
LAST-MODIFIED:20260403T163634Z
UID:10000087-1761816600-1761820200@nbio.uw.edu
SUMMARY:NBIO Presents: Ted Erclik\, PhD (University of Toronto Mississauga)
DESCRIPTION:Seminar information coming soon! \n Health Sciences G328 and Zoom
URL:https://nbio.uw.edu/event/nbio-presents-ted-erclik-phd-university-of-toronto-mississauga/
LOCATION:Health Sciences G-328
CATEGORIES:Seminar
ATTACH;FMTTYPE=image/jpeg:https://nbio.uw.edu/wp-content/uploads/2025/09/placeholder-image20191017_UW-Bothell-Campus-10_17_0317-scaled-e1760646849191.jpg
ORGANIZER;CN="UW NBIO":MAILTO:nbio@uw.edu
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